Ryze

Strengths

Use Overload's passive to optimize for maximum damage or maximum speed.
Spell Flux's short cooldown allows it to be used to spread Flux to many enemies.
Ryze can move and cast other spells while Realm Warp is charging without cancelling the portal.

Passive · Arcane Mastery — Ryze's spells deal extra damage based on his Bonus Mana, and he gains a percentage increase to his maximum Mana based on his Ability Power.
Q · Overload — Passively, Ryze's other basic abilities reset the cooldown of Overload and charge a rune. When Ryze casts Overload with 2 runes charged, he gains a brief burst of Move Speed. On cast, Ryze throws a charge of pure energy in a line, dealing damage to the first enemy struck. If the target has Flux on it, Overload deals extra damage and bounces to nearby enemies with Flux.
W · Rune Prison — Ryze traps a target in a cage of runes, damaging them and slowing their movement. If the target has Flux on it, they are instead rooted.
E · Spell Flux — Ryze releases an orb of pure magical power that damages an enemy and debuffs all nearby enemies. Ryze's spells have additional effects against the debuffed enemy.
Ultimate · Realm Warp — Passively, Overload deals even more damage against targets with Flux. On cast, Ryze creates a portal to a nearby location. After a few seconds, allies standing near the portal are teleported to the target location.

A suggested 5-lane lineup built around Ryze, based on hero partnerships and role synergy — not win rate.